TriO
NIPT onlyFTS & PE only
SingletonTwinsStandard NIPT (singleton or twins)Standard NIPT + 8 Microdeletion Syndromes (singleton only)
First Trimester Screening

Abdominal ultrasound: viability, growth, early anatomy, markers of chromosome differences (NT, FHR, DV, NB)*

Maternal serum: PAPP-A and hCG

 		✔
✔✘✘✔
Pre-Eclampsia Screening

(maternal blood pressure, serum PlGF, PAPP-A, history questionnaire)

 		✔
✔✘✘✔
NIPT: Chromosome differences -Trisomy 21 (Down syndrome), Trisomy 18, Trisomy 13

 		✔
✔✔✔✘
NIPT:  Sex chromosome differences (X, XXY, XXX, XYY)

 		✔ (optional)
Not available✔ (singleton only)✔✘
NIPT: Fetal sex(es)✔ (optional)
✔ (optional)✔✔✘
NIPT:

Microdeletion Syndromes		✔ 6 (optional)

22q11.2 del syndrome
Cri-du-chat syndrome
1p36 deletion syndrome
Prader-Willi syndrome
Angelman syndrome
Wolf-Hirschhorn syndrome
Not available✘ ✔ 8

22q11.2 del syndrome
Cri-du-chat syndrome

1p36 deletion syndrome

Prader-Willi syndrome

Angelman syndrome

Wolf-Hirschhorn syndrome
Jacobsen syndrome**
Langer-Giedion syndrome**

 		✘
Cost (CAD- no tax)$1000
$1250***$650$950$650